APOE4 Gene Test Genetic Test Kit Fenix Health Science

MTHFR Gene Test

Name: MTHFR Gene Test
Brand: Fenix Health Science
Price: 125.0 USD
Availability: InStock

$125.00

A simple at-home cheek swab that reveals your MTHFR genotype and estimated MTHFR activity, one of the most researched genes linked to methylation, brain chemistry, and overall neurological health.

Powered by GeneMetrics, this advanced DNA test analyzes over 800,000 genetic variants to generate clinically meaningful genetic insights from your unique genetic blueprint.

Start with the Basic MTHFR Report for focused insight into how your body processes folate and supports methylation chemistry related to attention, mood, and cognitive clarity. Or upgrade to the Methylation+ Panel (9 reports) for a broader view of the genetic pathways that influence methylation, inflammation, detoxification, micronutrient metabolism, sleep, emotional health, and long-term performance.

Choose Report(s) Basic MTHFR (1 Report) Methylation+ (10 Reports)

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Register your kit using the easy instructions
Complete the cheek swabs and return your sample vials using the included pre-paid mailer
Get your results in about 2 to 3 weeks delivered securely to your inbox
If at any time, you'd like to receive additional reports, you can upgrade for more genetic insights through the portal

Your MTHFR status
How your body processes folate
Your methylation tendencies
Personalized nutrition guidance and next steps

Why Use Fenix Gene Tests?

At-home cheek swab with easy instructions
No blood draw or clinic visit needed
Results in about 2 to 3 weeks
Personalized interpretation of your MTHFR status
Nutrition and lifestyle guidance based on genetics

MTHFR Gene Test

Basic MTHFR (1 Report)

At-Home Testing

Easy Collection

Secure Results

CLIA- & CAP-certified lab

HIPAA & GDPR standards

What's Included with our

1 Basic MTHFR Report

A focused genetic report centered exclusively on your MTHFR genotype and estimated enzyme activity.

This assessment includes:

Identification of whether you carry the common MTHFR variants (C677T and/or A1298C)
How your genotype may influence folate metabolism and methylation efficiency
An overview of how MTHFR supports homocysteine balance
Personalized nutrition and lifestyle considerations based on your genetic insight

Designed for individuals who want a targeted look at their MTHFR status and its biological significance.

What's Included with our

10 Methylation Reports

A comprehensive genetic panel that includes 68 genetic insights.

These assessments include:

Everything in the Basic Report
Expanded methylation pathway insights beyond MTHFR
Genes influencing folate metabolism, B12, and choline needs
Detoxification and glutathione-related pathways
Genetic factors related to attention and cognitive traits
Mood and emotional health patterns
Sleep duration and circadian-related tendencies
Micronutrient metabolism and nutrition-related pathways
Performance and longevity resilience markers
Inflammation & immune response patterns with CRP-related signals

Designed for individuals seeking a broader, systems-based view of the genes influencing methylation and long-term cognition.

Man swabbing cheek while taking a genetic test

Green DNA double helix icon on a white background

Why MTHFR Matters

The MTHFR gene helps convert folate into 5-MTHF, the active form your body uses to support DNA repair, neurotransmitter production, and healthy homocysteine levels.

When certain variants reduce enzyme efficiency, folate may not be processed as effectively. This can influence methylation and brain chemistry related to mood, focus, and inattention, especially when combined with other nutritional factors.

Understanding your MTHFR status can help guide more personalized nutrition decisions, including whether bioactive folate such as 5-MTHF may be a better fit than synthetic folic acid, along with other key nutrients that support methylation balance.

Learn More

MTHFR Test Details

MTHFR (Methylenetetrahydrofolate Reductase) is a gene that provides instructions for making an enzyme involved in processing folate (vitamin B9) and supporting methylation, a foundational biochemical process that influences DNA repair, neurotransmitter production, and homocysteine balance. Variations in this gene may influence how efficiently the MTHFR enzyme functions in the body. There are two common variants of MTHFR: C677T and A1298C. You inherit one copy of the gene from each parent, which helps determine your overall enzyme activity.

Scientific research has identified associations between certain MTHFR variants and differences in folate metabolism and methylation efficiency. For example, the C677T variant has been associated with reduced enzyme activity in some individuals. However, MTHFR status alone does not determine health outcomes. Many factors, including diet, lifestyle, and other genetic and environmental influences, contribute to overall wellbeing. This test is intended for informational and educational purposes and is not intended to diagnose, treat, cure, or prevent any disease.

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MTHFR testing provides information about your specific MTHFR genotype, including whether you carry common variants associated with differences in folate metabolism and methylation efficiency. Although MTHFR status does not diagnose or determine outcomes, it can offer helpful insight into how your body processes folate and regulates homocysteine levels.

For some individuals, this information can guide more intentional decisions around nutrition and supplementation. It may clarify whether bioactive folate, such as L-methylfolate (5-MTHF), is worth discussing as an alternative to synthetic folic acid.

People often choose MTHFR testing to:

Understand whether they carry common MTHFR variants
Make informed decisions about folate supplementation, including L-methylfolate
Personalize nutrition and lifestyle strategies
Explore how methylation may relate to mood, focus, and overall wellbeing
Have more informed discussions with healthcare providers

Research suggests that lifestyle and nutritional factors play an important role in methylation balance. Knowing your MTHFR genotype can help you make practical, informed choices aligned with your biology.

This test is intended for informational and educational purposes and does not diagnose, treat, cure, or prevent any disease.

Learn more

Your kit includes everything needed for simple at-home DNA collection and secure processing:

Inside the box:

2 sterile cheek swabs
2 collection vials
Biohazard specimen bag
Prepaid return mailer
Step-by-step collection instructions

Included with your purchase:

Secure registration and laboratory processing by GeneMetrics
Personalized MTHFR report(s)
Clear interpretations with easy-to-follow recommendations
Confidential delivery of your results

The process is designed to be convenient, secure, and easy to complete at home.

The collection process is designed to be simple, quick, and non-invasive.

Your kit includes a cheek swab that collects DNA from the inside of your mouth — no needles, no blood draw, and no lab visit required. You gently swab the inside of your cheek for a few seconds, following the step-by-step instructions included in the kit. The process is painless and typically takes just a few minutes from start to finish.

There’s no special preparation needed beyond avoiding food or drinks 60 minutes before swabbing, as directed in the instructions. Once complete, you place the swab into the provided container and mail it back using the prepaid packaging.

It’s a straightforward, non-invasive way to access advanced genetic insights — all from the comfort and privacy of your home.

Your genetic information is protected using strict privacy and security standards.

Your DNA is used only to run your test and generate your personal results. It is not sold, shared for advertising, or used for unrelated research purposes.

Testing and analysis are conducted by GeneMetrics, a clinical laboratory partner that operates under HIPAA and GDPR privacy standards. Your data is protected using multi-level encryption, and additional safeguards are in place to reduce risk.

To further protect your privacy:

Your personal identifying information is stored separately from your genetic data (data separation protocol).
Genetic data is maintained in an anonymized genome database, meaning it is not stored in a way that directly identifies you.
Results are shared only with you — and with your healthcare provider only if you request it.

Protecting your privacy and maintaining data security are core components of the testing process.

Teal DNA double helix on a pastel background

Take this test if you want to...

Have deeper insight into your methylation & folate metabolism
Get clarity if you’ve been told you “might have MTHFR”
Make informed choices about folate supplements
Support energy, mood, & focus with targeted nutrition
Access personalized wellness insights easily
Have more informed conversations with your doctors

1. Register Your Kit

Receive your kit and register it by simply scanning the QR code or visiting the site provided.

Person using a cheek swab with a blurred background

2. Swab Your Cheek

Avoid eating or drinking one hour before swabbing. Rotate each swab in each cheek 10-15 times.

3. Prepare Your Sample

Place prepared vials in the biohazard bag and the bag in the prepaid shipping package to be mailed.

4. Get Your Results

You will receive an email when your results are in (about 2-3 weeks once the samples have arrived).

Easy, At-home Testing

No lab visit, no appointments required—just a simple test you can take entirely at home, on your own schedule and in your own space.

Private and Secure Data

Your data is protected with advanced safeguards so your genetic information remains fully confidential and in your control.

Understandable Results

Your results are simply explained and don’t require medical interpretation—just straightforward insights you can use right away.

Personal Nutrition Insight

Use your genetic insights to personalize your nutrition and make lifestyle choices tailored specifically to your body’s needs.

Access Additional Genetic Insights

Upgrade Anytime

You can begin with a focused single-gene report , such as the basic MTHFR, and unlock additional genetic reports through the portal whenever you choose. Your initial cheek swab captures your full genomic dataset, so you do not need to submit another sample to access expanded reports.

Simply pay the difference between your current test and the additional report or panel you would like to add. You are never charged more for starting with a focused option and expanding later.

Expanded reports provide deeper genetic insights across multiple biological systems, including brain health and cognition, sleep patterns, nutrition and micronutrient needs, hormone pathways, inflammation response, detoxification capacity, cardiometabolic health, longevity, and performance-related genetics.

Results are delivered in approximately 2–3 weeks after your sample is received by the lab.
Yes, your genetic information is used only to run your test and generate your personal results—it is not sold, shared for advertising, or used for unrelated research. Testing is processed by GeneMetrics, a clinical laboratory partner that operates under HIPAA and GDPR privacy standards. Your data is protected using multi-level encryption, and GeneMetrics uses data separation (your personal details are stored separately from your genetic data) to reduce risk even further. Genetic information is stored in an anonymized genome database, meaning it is not kept in a way that directly identifies you. Results are shared only with you (and your provider if you request it).
Yes. You can unlock additional genetic reports anytime using the same test kit. No need to swab twice, just unlock the additional reports after your results are in.
No. The reports are designed to be easy to understand, but they are also practitioner-friendly if you choose to share the results with your doctor.

Register your kit immediately after receiving it.

Your barcode number is the only way to identify your sample. If it is not recorded and registered correctly, you will not receive your results.
To Register:
1. Scan the QR code included in your kit or visit: app.fenixhealthscience.com
2. Complete the registration form and enter:
  - Your name
  - Email address
  - A password (you create this)
  - Your 8-character barcode starting with “MR”
3. Carefully write down your barcode.
4. Take a photo of your registration code and keep it for your records.
Registration creates your account so you can access your results once they are available.
Step 1: Scan the QR code in your kit or visit app.fenixhealthscience.com to begin registration.
Step 2: Complete the registration form by entering your:
- Name
- Email address
- Password (you create this)
- 8-character barcode starting with “MR” or "FHS"
Important:
- Carefully write down your barcode.
- Take a picture of your registration code and keep it for your records.
This creates your account so you can view results once available.
For at least 60 minutes before collection, do NOT:
- Eat
- Drink (except plain water)
- Brush your teeth
- Use mouthwash
- Use oils
- Use oral analgesics
- Use adhesives
- Use tobacco or nicotine
Drinking plain water is okay.
Your results are generated through GeneMetrics’ in-house laboratory, which is CLIA- and CAP-certified—two of the highest standards for clinical lab quality and accuracy. The testing and reporting process is backed by a multidisciplinary team spanning genetics, molecular biology, bioinformatics, clinical research, and medical data science. Just as importantly, the interpretation system is continuously refined using current, peer-reviewed scientific research and validated sources. The end goal is to provide results that are both technically reliable and translated into clear, evidence-based insights you can actually use in clinical and wellness decisions.