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Many people now use fish oil and omega-3 supplements, and some even use the terms “fish oil” and “omega-3” interchangeably, but there is much more to understand. These products provide different forms of omega-3s, sourced from different places in nature, and they don’t work the same way in the body. This article explores fish oil and its primary benefits. It explains why certain advanced omega-3 products including Accentrate® Omega with LYSOVETA® LPC offer specialized brain-targeted benefits distinct from standard fish oil.
Fish oil supplements are dietary supplements made from the tissues of oily fish such as mackerel, salmon, herring, tuna, sardines, and wild-caught anchovies. These supplements contain beneficial omega-3 fatty acids, primarily EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), essential fats that support the heart, brain, eyes, and overall health. Think of these omega-3s as special building blocks that keep your body working smoothly.
Fish oil supplements are produced by extracting oil from fatty fish. This oil naturally contains large amounts of omega-3 fatty acids, which provide well-known health benefits, including support for cognition, mood and vision health.
Most people take fish oil as softgels (small, easy-to-swallow capsules), while some people prefer liquid fish oil (cod liver oil). Softgels are more popular because they offer convenience and less of a fishy taste.
People take “fish oil” and omega-3 supplements for different reasons—heart health, joint comfort, immune support, brain function, mood, and overall wellness. Because omega-3s play different roles across the body's systems, the “best fish oil supplement” depends on the reason a person is taking it.
However, when the goal is brain health, the most effective omega-3 supplement is not a fish oil supplement. Instead, research shows that the best option is an omega-3 product derived from krill, which naturally contains higher concentrations of phospholipid and LPC-bound omega-3s—the form the brain absorbs most efficiently. This is why Accentrate® Omega with LYSOVETA® LPC stands apart.
Accentrate® Omega with LYSOVETA® LPC is the best omega-3 supplement for brain health. Accentrate® is not a traditional fish oil supplement—it is an advanced omega-3 formulation. Omega-3s can come from several marine sources, including krill, which obtain their omega-3s directly from phytoplankton, the original source of all EPA and DHA in the marine food chain. Fish merely bioaccumulate these omega-3s over time.
This advanced omega-3 supplement uses innovative ingredients like LPC-EPA and LPC-DHA, sometimes referred to as LYSO-DHA and LYSO-EPA, providing:
Supporting your attention span
Supporting your memory
Supporting your mood
Thanks to its special formulation, the brain absorbs it six times better than regular fish oils. It achieves this by using a special transporter called lysophosphatidylcholine (LPC), which acts like a special delivery truck, carrying beneficial fats (EPA and DHA) directly to your brain tissue. This delivers it in a more targeted way to the nervous system.
Fenix Health developed its omega-3 product line to support the needs of different ages and body weights:
Accentrate® Omega: Specifically formulated for children under 110 pounds. It provides "Brain Ready™ Nutrition" using the advanced omega-3 fats, LPC-EPA and LPC-DHA. These healthy fats are attached to lysophosphatidylcholine (LPC). This delivery helps children's attention, memory, mood, and overall mental health. Children usually take one (1) softgel every day, either with or without food, or as a healthcare professional tells them.
Accentrate® Omega 110: Specifically formulated for teens and adults who weigh over 110 pounds. This formula includes the same highly effective fats, LPC-EPA and LPC-DHA. The serving size is tailored to support the brain function of larger individuals effectively. The usual dose is two (2) softgels daily, which can be taken with or without food, or as a doctor advises.
Accentrate® Omega Max: Accentrate® Omega Max serves individuals who have significant deficiencies in omega-3 in their bodies. This formula offers maximum delivery because the brain absorbs it so effectively, and it contains higher levels of EPA and DHA (the healthy omega-3 fats). Omega Max provides intensive brain support. It improves your attention, memory, emotion, and mood control. The recommended serving size is three (3) softgels daily, which may be taken with or without food, or as a doctor directs.
Fenix Health Science core principles have always included a commitment to using the most bioavailable nutrients. Fenix renewed its commitment by being the first company in the United States to include LYSOVETA® LPC in it’s products. Accentrate® Omega exemplifies Fenix’s commitment to innovation and science, providing a unique, effective supplement for mental clarity and emotional regulation through advanced, brain-targeted omega-3 fatty acids. They are certified dairy-free, soy-free, and gluten-free. With faster absorption and sustained effects, Accentrate® Omega is a premium supplement derived from marine sources, including krill, which naturally contain higher levels of phospholipid- and LPC-bound omega-3s..
Scientific research supports this unique ingredient, confirming that it reaches targeted tissues more effectively. It’s suitable for individuals seeking advanced omega-3 fish oil options beyond standard dietary supplements. Accentrate® Omega encourages consistent daily use over months for the best outcomes in cognitive function and mood support.
Omega-3 supplements provide essential omega-3 fatty acids, which may come from:
Fish oil
Krill oil
Algae
Other marine or plant oils
These supplements support heart, brain, and eye health, reduce inflammation, and help maintain immune function.
While fatty fish like salmon and mackerel contain omega-3s, many people turn to supplements to ensure they get enough of these essential fatty acids in their daily diet, especially if they don’t frequently eat seafood like cold water fish.
The main difference lies in the source:
Fish oil is derived from fatty fish and contains EPA and DHA in triglyceride or ethyl ester form.
Other omega-3 supplements may come from krill, algae, or plant-based sources. Krill and certain algae provide EPA and DHA in phospholipid (PC) form, which the body—especially the brain—absorbs more efficiently.
Accentrate® Omega differs from traditional krill oil supplements in its key ingredient and delivery method. While krill oil is a marine oil extracted from small crustaceans called krill and naturally contains omega-3 fatty acids EPA and DHA bound to phospholipids (PL), Accentrate® Omega uses a highly specialized form of omega-3s known as LYSOVETA® LPC. This lysophosphatidylcholine (LPC)-bound EPA and DHA formulation offers up to 6 times higher absorption of omega-3s directly to the brain compared to traditional fish oil
The omega-3s in Accentrate Omega come from sustainable, high-quality krill. And again, all omega-3s begin with phytoplankton, fish merely accumulate them from eating smaller organisms in the food chain. The krill oil is then refined into the advanced LPC-bound EPA and DHA. This method ensures that your body absorbs the fats far better than it absorbs plant oils like flaxseed oil or canola oil, making Fenix Health's products the most effective way to get these essential fatty acids for your brain and overall health. LYSOVETA® LPC technology represents a leap forward from traditional fish oil supplements because it improves delivery and efficacy (how well it works) while maintaining strict standards for purity and safety.
Fish oil is often considered the traditional form when it comes to omega-3 supplementation. However, not all fish oil supplements are the same. The primary types of omega-3s found in fish oil are:
EPA is one of the most well-known omega-3 fatty acids, primarily associated with heart health and inflammation reduction. It has been shown to have a beneficial effect on reducing triglycerides, supporting blood pressure levels, and improving overall cardiovascular health. EPA is also connected to improvements in mental health and emotional well-being.
DHA is the most abundant omega-3 in the brain, and it’s relevant in cognitive function and mental clarity. It supports brain health, cognitive development in children, and maintains mental function throughout adulthood, helping to prevent cognitive decline. DHA is also crucial for eye health, contributing to visual development and preventing degenerative diseases like macular degeneration. It’s especially important for prenatal health.
ALA is an omega-3 fatty acid found in plant-based foods, like flaxseed and chia seeds. While ALA is beneficial, it must be converted into EPA and DHA by the body to provide the same health benefits. However, this conversion process is inefficient, which is why fish oil supplements are often recommended for those looking for a direct source of EPA and DHA.
As one of the most potent sources of omega-3 fatty acids, fish oil supplements offer numerous health advantages, including:
Many people are familiar with fish oil’s benefits of supporting a healthy heart and blood vessels (cardiovascular support). Research shows that EPA and DHA lower the fat in your blood called triglycerides and decrease the chance of developing heart disease (Cleveland Clinic). Evidence published in the New England Journal of Medicine has found that taking fish oil supplements regularly can also help your body maintain healthy heart and cholesterol levels.
Omega-3s, especially polyunsaturated omega-3s are essential in maintaining brain function, as the brain is largely composed of fat, and omega-3s are necessary for brain cell structure. DHA in particular is a polyunsaturated omega-3 that is a major component of the brain’s gray matter and is involved in memory, learning, emotion, and mood regulation. Accentrate® Omega with LYSOVETA® LPC, with its superior brain-targeted absorption, can support cognitive development and help maintain brain function in adults.
Fish oil fights inflammation (swelling and redness) and eases the discomfort that comes with conditions like rheumatoid arthritis and other joint problems. The omega-3 fats in fish oil reduce certain proteins called inflammatory cytokines that cause pain and swelling. Fish oil can improve how easily your joints move and increase your comfort levels by decreasing these proteins (Arthritis Foundation).
DHA is also essential for maintaining eye health, particularly for the retina. Research has shown that omega-3 fatty acids can support visual development and may protect against age-related eye conditions like macular degeneration (Effects of Omega-3 Fatty Acids on Eye Health). LYSO-DHA is a preferred nutrient for vision health in light of its superior absorption to the retina.
Omega-3s in fish oil can benefit the skin by reducing inflammation and promoting hydration. Studies have shown that fish oil can help manage conditions like eczema and psoriasis, improving the appearance of the skin and reducing irritation (Healthline).
Researchers study omega-3 fatty acids because they can support mental health (Grosso et al.). While these fats cannot cure illnesses like depression or anxiety, they may improve your overall mood, decrease feelings of anxiety, and promote better emotional control. Fish oil can also support clear thinking by reducing mental "brain fog" and improving your ability to focus. LYSO-DHA is a preferred nutrient for brain health in light of its superior absorption across the blood brain barrier.
Not all fish oil supplements are created equal. It’s important to consider several factors to ensure you're getting a quality fish oil supplement. Here are some things to look for:
Purity and Quality: Choose a supplement that’s third-party tested to ensure it is free from contaminants such as mercury, heavy metal contamination, and PCBs. Look for certifications from organizations like the Marine Stewardship Council (MSC) to verify sea-certified sustainable sourcing from wild-caught fish. Information on safety is often reviewed by organizations like the National Center for Complementary and Integrative Health.
Omega-3 Content: Look for supplements that contain a high amount of EPA and DHA. Accentrate® Omega provides an optimal combination of these essential omega-3s in their advanced LPC form, offering superior absorption.
Bioavailability: Supplements formulated with higher bioavailability, such as Fenix Health's LYSOVETA® LPC, are more efficiently absorbed by the body, leading to better results. Clinical verification is often sought through randomized controlled trials.
Formulation and Dosage: Depending on your needs, you may want to choose between softgels or liquid dose fish oil (sometimes with a flavor like mixed berry). Make sure to follow the recommended dosage for optimal benefits.
If an individual is looking at omega-3 fatty acid supplementation for brain health or vision health, Fish Oil Supplements may not be adequate. LYSO-DHA is a preferred nutrient for brain health in light of its superior absorption across the blood brain barrier.
Fish oil is generally safe for most people, but it can cause side effects in some individuals. Common side effects include:
Fishy aftertaste or fish burps
Digestive issues, which involve nausea or diarrhea
High doses increase the risk of bleeding, especially if you take blood-thinning medications (like Warfarin or aspirin)
To minimize side effects, start with a low dose and gradually increase it. If you experience any adverse reactions, consult with a healthcare professional before continuing.
Fish oil supplements are an excellent source of omega-3 fatty acids, which offer numerous benefits for heart health, brain function, mental clarity, and overall well-being. When choosing a supplement, it’s essential to prioritize quality supplements and also consider alternatives that offer higher bioavailability, such as Fenix Health’s Accentrate® Omega. With its advanced LYSOVETA® LPC formulation, Accentrate® Omega is the best fish oil supplement for those looking to enhance cognitive function, mood, memory, and brain health.
Remember, while fish oil supplements are important for your health, it’s always important to complement them with a balanced diet and a healthy lifestyle. Consider consulting with health professionals for personalized recommendations and to ensure that fish oil supplements are a good fit for your specific needs.
Choose the best fish oil supplement to support your health today and experience the many benefits omega-3 fatty acids have to offer!
Arthritis Foundation. "Omega-3 Fatty Acids for Your Health." Arthritis Foundation, 2024.
Cleveland Clinic. "Omega-3 Fatty Acids & the Important Role They Play." Cleveland Clinic, 2024.
Grosso, G. et al. "Omega-3 fatty acids and the treatment of depression: a review of scientific evidence." Marine Drugs, vol. 13, no. 12, 2015, pp. 6950–6973.
Healthline. "Does Fish Oil Have Benefits for Eczema?" Healthline Media, 2025.
NIH (National Institutes of Health). "Effects of Omega-3 Fatty Acids on Eye Health: Summary." Agency for Healthcare Research and Quality (US), 2015.
Yalagala, Poorna C. R., et al. "Enrichment of brain docosahexaenoic acid (DHA) is highly dependent upon the molecular carrier of dietary DHA: lysophosphatidylcholine is more efficient than either phosphatidylcholine or triacylglycerol." The Journal of Nutritional Biochemistry, vol. 72, 2019, pp. 11–17.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
