APOE4 Report Upgrade
The APOE4 Report Upgrade is for individuals who have already sent in a gene test kit and received a report, but now want to add data on APOE4 to their results. This digital upgrade allows you to unlock your specific APOE genotype (ε2, ε3, ε4 status) without the need for another cheek swab. This report identifies your inherited risk for late-onset cognitive decline and memory loss and provides actionable insights into how your body manages cholesterol and inflammation.
To learn how your genetic information is protected, please review our Genetic Testing Privacy Statement.
Product details and reporting options are subject to change by the manufacturer and may differ from the information shown on this site. Always verify instructions and warnings on the actual product label before use. This content is for reference only and does not constitute medical advice or a diagnosis. The genetic reports are for reference only and do not constitute medical advice, a diagnosis, or a clinical genetic consultation. We recommend consulting a licensed genetic counselor or healthcare professional to interpret your results within the context of your personal and family medical history. Genetic reports have not been evaluated by the FDA and are not intended to diagnose or cure any health condition.
Why Use Fenix Gene Tests?
1 Basic APOE Report
A focused genetic report centered exclusively on your APOE genotype and allele status.
This assessment includes:
- Identification of whether you carry 0, 1, or 2 copies of APOE4 and your status
- How your genotype relates to lipid metabolism and inflammatory response
- An overview of how APOE influences the brain
- Personalized lifestyle strategies based on your genotype
Designed for individuals who only want a targeted look at their APOE status and its biological significance.
Why APOE4 Matters
APOE (Apolipoprotein E) is a gene that provides instructions for making a protein involved in cholesterol transport and normal brain function. Variations in this gene may influence how the APOE protein works in the body. There are three common variants of APOE: E2, E3, and E4. You inherit one variant from each parent, resulting in one of six possible combinations: E2/E2, E2/E3, E2/E4, E3/E3, E3/E4, & E4/E4
Scientific research has identified associations between certain APOE variants and differences in cognitive health risk and Alzheimer’s. For example, E4 is associated with higher risk, while E2 may offer some protective effect. However, APOE status alone does not determine health outcomes. This test is intended for informational and educational purposes and is not intended to diagnose, treat, cure, or prevent any disease.
APOE testing provides information about your specific APOE genotype, including whether you carry the E4 variant that research has associated with differences in cognitive aging risk.
Although APOE status does not diagnose or determine outcomes, it can offer useful insight into how your body may respond to factors such as inflammation, cholesterol metabolism, and long-term brain aging. For some individuals, especially those with a family history of Alzheimer’s or dementia, this information can help guide earlier and more intentional health decisions.
People often choose APOE testing to:
- Understand whether they carry zero, one, or two copies of E4
- Personalize nutrition and lifestyle strategies based on genetic insight
- Prioritize brain-supportive habits such as omega-3 intake, metabolic health, exercise, and sleep
- Have more informed discussions with healthcare providers
Research suggests that lifestyle factors play an important role in long-term cognitive health. Knowing your APOE genotype can help you make practical, informed choices aligned with your individual biology.
This test is intended for informational and educational purposes and does not diagnose, treat, cure, or prevent any disease.
Your genetic information is protected using strict privacy and security standards.
Your DNA is used only to run your test and generate your personal results. It is not sold, shared for advertising, or used for unrelated research purposes.
Testing and analysis are conducted by a clinical laboratory partner that operates under HIPAA and GDPR privacy standards. Your data is protected using multi-level encryption, and additional safeguards are in place to reduce risk.
To further protect your privacy:
- Your personal identifying information is stored separately from your genetic data (data separation protocol).
- Genetic data is maintained in an anonymized genome database, meaning it is not stored in a way that directly identifies you.
- Results are shared only with you — and with your healthcare provider only if you request it.
Protecting your privacy and maintaining data security are core components of the testing process.
Take this test if you...
- Want insight into your genetics related to brain health
- Have a family history of dementia or Alzheimer’s
- Want to be proactive about long-term cognitive wellness
- Want personalized nutrition and lifestyle guidance
- Want actionable insights—not just raw genetic data
Frequently Asked Questions
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Yes, your genetic information is used only to run your test and generate your personal results—it is not sold, shared for advertising, or used for unrelated research. Testing is processed by a clinical laboratory partner that operates under HIPAA and GDPR privacy standards. Your data is protected using multi-level encryption and data separation (your personal details are stored separately from your genetic data) to reduce risk even further. Genetic information is stored in an anonymized genome database, meaning it is not kept in a way that directly identifies you. Results are shared only with you (and your provider if you request it).
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Yes. You can unlock additional genetic reports anytime using the same test kit. No need to swab twice, just unlock the additional reports after your results are in.
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No. The reports are designed to be easy to understand, but they are also practitioner-friendly if you choose to share the results with your doctor.
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Your results are generated through a CLIA- and CAP-certified laboratory, two of the highest standards for clinical lab quality and accuracy. The testing and reporting process is backed by a multidisciplinary team spanning genetics, molecular biology, bioinformatics, clinical research, and medical data science. Just as importantly, the interpretation system is continuously refined using current, peer-reviewed scientific research and validated sources. The end goal is to provide results that are both technically reliable and translated into clear, evidence-based insights you can actually use in clinical and wellness decisions.
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