The Best Brain Supplements: Do They Really Enhance Cognitive Function?

Mental clarity, emotional balance, and sustained focus are not jargon; they are vital aspects of a thriving mind. Cognitive performance is intricately tied to several modifiable lifestyle and nutritional factors, particularly in the context of chronic cerebral disorders and mild cognitive and behavioural disturbances.
Fish oil supplements, which are rich in omega-3 fatty acids, improve brain health and lower inflammation. These benefits also apply to healthy adults seeking to improve mental clarity and cognitive resilience. Key nutrients, like folate and B vitamins, also aid normal neurochemical balance and cellular energy metabolism.
At Fenix Health Science, we provide formulas that support mental function. Let's explore the best brain supplements designed to offer a nutritional foundation for mental clarity and memory.
What Supplements Are Good For the Brain?
Meet our products at the forefront of nutritional cognitive support. These supplements are carefully designed to help promote focus, mood regulation, and emotional steadiness. These products help maintain cognitive function for both adults and children.
Accentrate® Neuro
Accentrate® Neuro is a precision-formulated vitamin B complex that delivers active, bioavailable B vitamins designed to support mental function and emotional balance. It’s specially tailored for individuals under 110 lbs. It incorporates clinically studied ingredients like L-methylfolate calcium (folate), Pyridoxal-5-phosphate (Vitamin B6), Methylcobalamin (Vitamin B12), Riboflavin-5-phosphate (Vitamin B2), and Niacinamide (Vitamin B3). Each component is selected to offer optimal bioavailability. Accentrate® Neuro also helps the body use nutrients more effectively without the need for metabolic conversion.
How It Works:
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It provides Brain Ready™ vitamins in bioavailable forms
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It supports normal neurotransmitter function (dopamine & serotonin)
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It requires no activation by the liver or kidneys, allowing faster nutrient utilization
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It is designed to work synergistically with Accentrate® Omega for enhanced support
Shop Accentrate® Neuro now.
Accentrate® Neuro 110
Accentrate® Neuro 110 is the next-step solution for individuals over 110 lbs. seeking brain support through essential B vitamins. Its formulation mirrors Accentrate® Neuro, using active, bioavailable versions of B6, B12, folate, B2, and B3 to help nourish the nervous system and maintain emotional balance.
How It Works:
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It delivers Brain Ready™ vitamins to support neurotransmitter function
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It is for bodies over 110 lbs.
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It does not require the need for liver or kidney conversion
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It is best used alongside Accentrate® Omega 110 for comprehensive support
Shop Accentrate® Neuro 110 now.
Accentrate® Neuro-X
Accentrate® Neuro-X is an alternative for individuals who may be sensitive to methylated or folate-containing supplements. It contains active, brain-ready B vitamins to support emotional stability and mental clarity. It's especially helpful for those with MTHFR gene variants or overmethylation sensitivities, who may struggle with folate metabolism.
How It Works:
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It is formulated with lower amounts of folate
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It has no methylated vitamin B12
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It supports normal neurotransmitter regulation
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The ingredients in bioavailable forms allow for direct absorption
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It can be combined with an Omega™ supplement for optimal results
Shop Accentrate® Neuro-X now.
Accentrate® Minerals
Accentrate® Minerals contains chelated magnesium, zinc, and iron to help support cognitive balance in those under 110 lbs. Its chelated mineral format supports easier absorption and gentle digestion – ideal for children or those with sensitive stomachs.
How It Works:
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It includes chelated magnesium, zinc, and iron
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It supports proper neurotransmitter regulation
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It is less likely to cause gastrointestinal discomfort
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It is developed for individuals under 110 lbs.
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Accentrate® Minerals 110
Accentrate® Minerals 110 is designed for teens and adults over 110 lbs. With chelated forms of magnesium, zinc, and iron, it supports attention, memory, and mental clarity.
How It Works:
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It contains chelated minerals for improved absorption
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It is designed to minimize digestive issues
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It supports cognitive functions such as memory and focus
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It is ideal for daily use in adults and older children
Shop Accentrate® Minerals 110 now.
Accentrate® Omega
Accentrate® Omega with LYSOVETA® LPC offers targeted omega-3 support for kids under 110 lbs. With a unique LPC-EPA and LPC-DHA formulation, it is designed to deliver six times more omega-3 absorption to the brain than traditional fish oils.
How It Works:
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It provides Brain Ready™ omega-3s in phospholipid form
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LPC-EPA and LPC-DHA support mood, attention, and memory
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It produces superior brain absorption compared to fish oil
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It is designed for children under 110 lbs.
Shop Accentrate® Omega now.
Accentrate® Omega 110
Accentrate® Omega 110 brings the same breakthrough omega-3s to adults and teens over 110 lbs. It offers nutritional support for emotional steadiness and cognitive clarity through its advanced LPC-EPA and LPC-DHA.
How It Works:
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It delivers omega-3s with six times more brain absorption than fish oil
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It is designed for teens and adults over 110 lbs
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It supports memory, mood, and attention
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It combines well with Neuro™ 110 and Minerals™ 110
Shop Accentrate® Omega 110 now.
Accentrate® Omega Max
Accentrate® Omega Max is the highest-strength omega-3 supplement in the Accentrate® line. With more EPA and DHA in Brain-Ready™ LPC form, it’s designed for maximum cognitive support and omega-3 brain accretion—ideal for those with deficiencies needing enhanced absorption.
How It Works:
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It has the highest dose of LPC-EPA and LPC-DHA
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It supports cognitive performance and emotional resilience
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It produces 6x better brain absorption than standard fish oil
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It is ideal for those seeking potent, targeted support
Shop Accentrate® Omega Max now.
How Dietary Supplements Support Brain Health in Adults
Emerging research highlights a compelling connection between cardiovascular and cognitive health. High blood pressure can damage small blood vessels, impairing nutrient delivery and leading to a high risk of cerebral disorders. Addressing these vascular factors is therefore important in both reducing the risk of cognitive decline and supporting mental performance.
Key supplements that may aid in this dual function include:
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Fish Oil Supplements: They are rich in EPA and DHA, and have demonstrated the ability to support healthy blood pressure while also supporting memory and mood.
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Ginkgo Supplements: They have been used in traditional Chinese medicine for centuries, and they are believed to improve circulation, particularly cerebral blood flow. Some evidence also suggests it may help reduce behavioral disturbances in patients with dementia, though results are mixed and dose-dependent (Gauthier & Schlaefke, 2014)
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Magnesium, Vitamin D, and Folic Acid: They contribute to vascular relaxation, proper neurotransmitter regulation, and methylation processes, all of which are central to normal mental and cardiovascular function.
It is important to note that these brain health supplements should be taken as a complement to, not in replacement of, a medical practitioner’s suggested protocol.
Understanding Cognitive Decline: What Causes It and How to Support Brain Health Naturally
Cognitive decline, including conditions like mild cognitive impairment and dementia, is increasingly recognized as an issue rooted in aging, genetics, and lifestyle. While some decline is expected as part of aging, early and mid-life behaviors can significantly influence long-term outcomes. Studies continue to emphasize the role of modifiable risk factors, particularly cardiovascular risk factors like hypertension and elevated cholesterol, in accelerating neurodegeneration.
One approach to preventing cognitive decline involves a combination of lifestyle strategies and nutritional support:
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Regular physical activity, especially aerobic exercise, improves blood flow to the brain and has been shown in numerous controlled trials to improve cognitive function.
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Mental stimulation through learning, socializing, and problem-solving helps build cognitive reserve.
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Dietary interventions like the MIND and Mediterranean diets emphasize the intake of omega-3-rich fish, leafy green vegetables, and foods high in antioxidants such as vitamin E and vitamin C. These nutrients help protect neurons from oxidative stress.
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Mind-body practices, including mindfulness and stress management, reduce cortisol levels and inflammation that can damage some structures over time.
The Role of Supplements
A well-rounded diet may be foundational, but certain nutrients may not be obtained from food alone, especially in older adults or those with dietary restrictions. Advanced Omega 3 supplements provide bioavailable B vitamins (including folic acid), LPC-form omega-3s, and antioxidants like vitamin E for neuroprotectivity.
Vitamin E, specifically alpha-tocopherol, has been shown in controlled trials to slow functional decline in patients with mild to moderate Alzheimer's, supporting its relevance even in early-stage cognitive deterioration (Dysken et al., 2014).
The Role of B Vitamins in Maintaining Neurological Health
B vitamins play a fundamental role in maintaining neurological health by supporting mental clarity, steady energy levels, and emotional balance.
Key B vitamins and their functions:
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B6 (Pyridoxal-5-phosphate): It helps in the creation of neurotransmitters such as serotonin and dopamine.
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B12 (Methylcobalamin): It supports nerve cell health and myelin sheath production.
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B9 (L-methylfolate): It assists in DNA synthesis and normal neural communication.
Brain supplements like Accentrate® Neuro deliver these vitamins in their active, readily absorbed forms to aid me and offer direct support.
Ginkgo Biloba and Blood Flow: A Natural Ally for Brain Health
Ginkgo biloba, an ancient herbal extract, has long been used for its potential to support circulation and cognitive performance. It may support blood flow and help with occasional memory concerns in aging adults, calm stress, maintain mood, and promote overall mental clarity.
When combined with other heart-healthy practices like regular aerobic exercise, whole grains, and a diet low in saturated fats, certain supplements like ginkgo biloba can support both cardiovascular and brain health. However, ginkgo should be used cautiously and discussed with a healthcare provider, especially if you're on blood-thinning medications.
Can Dietary Supplements Influence Blood Pressure and Brain Function?
Certain supplements and nutrients are known to influence both cardiovascular and cognitive health.
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Omega-3 fatty acids, particularly eicosapentaenoic acid (EPA), can help enhance communication between brain cells.
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Magnesium supports the relaxation of blood vessels and plays a role in regulating nerve transmission and cell membranes.
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Vitamins D and B support both vascular integrity and neurotransmitter activity, which can balance mood and support attention.
Recent systematic reviews and research from institutions such as the National Institutes of Health highlight the potential benefits of combining supplements with lifestyle habits like regular physical activity, enough sleep, and diets such as the MIND diet, a nutritional plan endorsed by the Alzheimer's Association for its focus on brain-healthy foods and its association with a lower risk of cognitive decline.
While brain health supplements alone shouldn’t replace medical guidance or healthy living, they can complement a well-rounded strategy for those aiming to support memory, promote eye health, and sustain long-term cognitive resilience.
Conclusion
Supporting brain function begins with understanding what your body needs and supplying it with the right nutrients. Products like those in Fenix Health Science's Accentrate® line combine advanced formulations with bioavailable nutrients, designed to enhance cognitive function, focus, mood, and support emotional balance. These products offer scientific ways to nurture long-term brain health, especially in older adults.
Reference List
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BMC Public Health. "Physical activity and the risk of cognitive decline: a systematic review and meta-analysis of prospective studies."
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PubMed Central. "Impact of the MIND diet on neurodegenerative delay."
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IOCDF. "Reduce Anxiety Through Exercise, Sleep, Diet, Mindfulness and other Stress Relieving Measures."
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Food for the Brain. "Omega-3 and B vitamins in Alzheimer’s prevention."
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Gauthier, S., & Schlaefke, S. (2014). Efficacy and tolerability of Ginkgo biloba extract EGb 761® in dementia: a systematic review and meta-analysis of randomized placebo-controlled trials. Clinical Interventions in Aging, 9, 2065–2077.
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Dysken, M. W., Sano, M., Asthana, S., Vertrees, J. E., Pallaki, M., Llorente, M., ... & ADCS. (2014). Effect of vitamin E and memantine on functional decline in Alzheimer disease: the TEAM-AD VA cooperative randomized trial. JAMA, 311(1), 33–44.
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"Research, including controlled trials, suggests that moderate caffeine consumption may improve aspects of working memory and reaction time, particularly in fatigued individuals (Hogervorst et al., 1999)."