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We all know that omega-3 fatty acids have always been considered an important nutrient for human health, right? But are you sure it's really helping you? Most people who take omega-3s are told to “be patient” — results usually take months to notice, if they come at all. But what if waiting wasn’t necessary? What if there were a way to feel the difference sooner, because your body and brain actually get the omega-3s you’re taking? Some omega-3 supplements are not easily absorbed by our bodies, which makes them less effective.
This is why Aker Biomarine developed Lysoveta®, an improved omega-3 formulation, to ease absorption and deliver nutrients where they're needed most in the body (Aker BioMarine, n.d.). Lysoveta® is a breakthrough in supplementation because it uses a specific transport mechanism that delivers the needed omega-3s into the brain and body more effectively.
In this guide, we'll talk about the science behind Lysoveta®, how it works, and how it can help your brain and cognitive health.
At Fenix Health Science, we believe in providing advanced solutions for your brain health. That's why we’ve built our signature product, Accentrate® Omega, around the innovative Lysoveta® LPC ingredient (Fenix Health Science, LLC). We formulated Accentrate® Omega with Lysoveta®'s LPC that contains LPC-DHA and LPC-EPA, which uses the MFSD2a transporter, a specialized carrier protein in your body, for direct absorption into the brain. We offer a supplement that provides up to six times higher absorption to the brain than standard fish oil. This superior absorption is the primary reason our product can deliver the health advantages you’re looking for.
We’re also committed to quality, which is why our Lysoveta®'s LPC is extracted and purified in the USA and produced in a facility that adheres to strict cGMP standards. We’re proud to have created a product that offers superior support for your brain health.
Lysoveta® is a revolutionary omega-3 ingredient that offers a superior bioavailable form of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) bound to Lysophosphatidylcholine (LPC)--backed by science. It's different from regular omega-3 supplements because it delivers essential fatty acids directly to your brain and eyes, the way your body naturally does..
Lysoveta® LPC is designed to be transported by a natural protein in the body called Major Facilitator Superfamily Domain containing 2a (MFSD2A). Lysoveta® LPC ensures that EPA and DHA are absorbed and delivered directly to the tissues that need them by leveraging this existing transport system. This unique mechanism helps overcome the problem of low bioavailability that has affected many omega-3 supplements in the past.
LPC is a phospholipid molecule that helps in the formation of cell membranes, especially neurons. They increase omega-3 fatty acids like EPA and DHA’s ability to penetrate your blood-brain barrier (BBB). It does this because they are the lipids your body makes naturally. LPC is nature’s plan A. Fish oil is nature’s plan B. This capacity to cross your BBB is important because it allows omega-3s to reach your brain directly. As a result, these omega-3s help protect the neurons and help with cognitive function.
As a supplement, omega-3s are attached to LPC making them bioavailable than other forms, such as triglycerides or free fatty acids. Because LPC works the way nature intends, it’s easier for your body to absorb and use omega-3s, particularly DHA, which is crucial for memory, thinking, and mood regulation in brain tissue.
DHA and EPA are two of the most important omega-3 fatty acids. These fats are necessary for our bodies to function. You can get them from food or supplements.
Both EPA and DHA offer many health benefits for the brain, mood, and cognitive function. Note that DHA is a major component of our brain and retina, and it makes up a large part of the structural lipids in the brain. It's important for keeping memories, supporting focus, and overall cognitive function.
On the other hand, EPA is the main fatty acid that controls inflammation and keeps our heart healthy. It also keeps our mood stable and makes us more resilient to stress. EPA and DHA work together to protect our brain's health and reduce the risk of cognitive decline as we age.
The technology behind Lysoveta® is based on the MFSD2A transporter, a protein on our blood-brain barrier that’s natural purpose is to move DHA directly into the brain (Nguyen et al., 2014). Because our BBB makes it hard for many supplement forms, such as triglyceride or free fatty acids, to reach the brain, the development of Lysoveta® is a huge success. Lysoveta® utilizes LPC-DHA because it's the natural form that our brain uses for neuronal membrane formation and function. The ability of LPC-DHA to cross the BBB efficiently makes Lysoveta® LPC the most bioavailable form of omega-3 supplements on the market.
Traditional krill oil has been a common source of omega-3 because it includes EPA and DHA acids, and our body easily absorbs them more than those obtained from fish oil. However, krill oil still has problems when it comes to delivering these fatty acids efficiently to our brain and other important tissues.
The main difference between Lysoveta® and regular krill oil is how the omega-3s are delivered to our brain. Krill oil has EPA and DHA in phospholipid, but Lysoveta® uses LPC to hold the omega-3s together. This LPC-bound form is the most bioavailable form of omega-3, which means that our brain absorbs it more efficiently, and it can easily cross our BBB. For a supplement to be effective for brain health, it must be able to cross this barrier to deliver its nutrients directly to the brain cells where they are needed. Without crossing the barrier, the supplement cannot provide cognitive benefits.
The MFSD2A transporter is an important protein that helps LPC-DHA get across our BBB efficiently. However, as we age, the level of the MFSD2A transporter decreases, which contributes to cognitive decline. Lysoveta® LPC helps overcome this age-related reduction in transport by providing EPA and DHA in the LPC-bound form. Lysoveta® doesn’t increase the level of the MFSD2A transporter, but ensures our brain receives the vital nutrients it needs to remain protected and maintain strong cognitive function throughout life. It’s able to do this because of its unique LPC-bound form.
Lysoveta® LPC uses the body's own transport mechanism to make sure that EPA and DHA reach our brain and other tissues that need them. It makes sure that omega-3s are directly delivered across our BBB by binding them to LPC. Our BBB is a barrier that keeps other types of omega-3s from getting to the brain efficiently. This delivery system of binding omega-3s to LPC results in:
Better absorption of EPA and DHA in our brain and eye tissues.
Increased support by providing cognitive and visual health benefits.
Reduced dosage, since Lysoveta® LPC is a more efficient supplement than traditional omega-3s, a smaller amount can provide the same or better benefits. Smaller dose, smaller pill.
Lysoveta® LPC has a lot of potential to keep the brain healthy and manage cognitive decline. Clinical studies explore and propose that LPC-DHA can:
Help us learn and remember things. (Guesnet et al., 2018).
Help manage our emotions and deal with stress. (ID.)
Help manage cognitive degeneration that comes with age. (ID.)
Help improve focus and overall brain function (ID.)
Lysoveta® LPC is great for:
Those concerned about age-related cognitive decline.
Those who want to improve memory, focus, and brain function.
Pregnant women who want to support their child's brain health.
Those who are mentally tired and want to improve their mood.
Individuals who don't eat a lot of fish.
Lysoveta® LPC is derived from Antarctic krill from Aker BioMarine, a leading harvester of krill from the Southern Ocean, located off the coast of Antarctica, which developed the ingredient. The team emphasizes its commitment to sustainable and ethical sourcing practices, making sure that its krill is obtained in an environmentally-friendly manner. Lysoveta® is also devoid of GMOs and allergens, so customers can be sure they’re getting a clean, high-purity supplement.
The krill Aker BioMarine uses in producing Lysoveta® LPC is the same Antarctic krill that is used for traditional krill oil. The difference lies in its processing and purification. Note that Lysoveta® LPC is not raw krill oil. It’s a highly refined and concentrated ingredient derived from krill oil, which is processed to create the unique LPC-bound omega-3s.
So, while the source is the same, the final product is chemically different and is designed for a specific purpose: better delivery to the brain.
Lysoveta® LPC has achieved a New Dietary Ingredient (NDI) status in the U.S. (U.S. Food and Drug Administration, 2023). This is a step forward in terms of regulations. For a company to legally sell a product containing a new dietary ingredient, it must submit a New Dietary Ingredient Notification (NDIN) to the FDA at least 75 days before marketing the product. This notification must provide the FDA with information that demonstrates the manufacturer's conclusion that the supplement is "reasonably expected to be safe." Therefore, for Lysoveta LPC, achieving NDI status means that its manufacturer successfully provided the necessary evidence of safety to the FDA and is now permitted to legally market its ingredient in the United States.
The Food and Drug Administration’s (FDA) approval of Lysoveta® means that it’s a safe and effective omega-3 supplement for adults. The NDI approval proves that LPC-DHA is an effective way to improve brain health and cognitive performance.
Lysoveta® LPC is an improved omega-3, representing the next generation in the field of supplementation. It uses LPC-bound omega-3s to provide the most accessible form of EPA and DHA, making sure they go directly to your brain and other important tissues. Lysoveta® LPC is the best omega-3 supplement on the market because it focuses on sustainability, effectiveness, and bioavailability.
Lysoveta® LPC is a revolutionary new omega-3 supplement that provides a highly bioavailable form of EPA and DHA. These omega-3s are directly transported to our brain for maximum efficiency because of their ability to support brain health, cognitive function, and neuroprotection. Lysoveta® is the perfect choice for those who want to improve their cognitive function and brain health before and as they get older.
Aker BioMarine. (n.d.). Lysoveta®: A new delivery platform for omega-3s.
Fenix Health Science. (n.d.). Accentrate® Omega.
Guesnet, P., Delattre, J., Alix, C., Drouet, E., & Lallemand, A. (2018). Role of Dietary and Endogenous DHA in Brain Development and Function: A Review of the Literature. Nutrients, 10(12), 1957
Nguyen, L. N., Ma, D., Shui, G., Wong, P., Cazenave-Gassiot, A., Zhang, X., ... & Silver, D. L. (2014). Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid. Nature, 503(7477), 503-506.
U.S. Food and Drug Administration. (2023, August 11). Aker BioMarine achieves NDI status for brain health ingredient. Nutraceuticals Business Review.
